Note 52c

We can also predicate :  'Socrates is rational '  (here we predicate a difference of an individual). This is allowed, because this predication can be the conclusion of a syllogism :

Socrates is a human being    (predicating a species of an individual)
A human being is rational     (predicating a difference of a species)
Therefore :
Socrates is rational          (predicating a difference of an individual).

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